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原发性高血压三个肾素亚组中肾素依赖性和钠依赖性的测定

Determination of renin-dependency and sodium-dependency in the three renin sub-groups of essential hypertension.

作者信息

Gavras H, Ribeiro A, Brunner H R, Gavras I

出版信息

Clin Sci Mol Med Suppl. 1976 Dec;3:197s-200s. doi: 10.1042/cs051197s.

DOI:10.1042/cs051197s
PMID:1071607
Abstract
  1. In all three renin sub-groups of essential hypertension, the state of sodium balance determines the degree of participation of the renin-angiotensin system in sustaining high blood pressure. 2. Even the low-renin type can become renin-dependent when sufficient sodium depletion has bee achieved. 3. The main difference between patients of these sub-groups appears to be their variable capacity to become depleted of sodium under standard dietary regimens.
摘要
  1. 在原发性高血压的所有三个肾素亚组中，钠平衡状态决定了肾素-血管紧张素系统在维持高血压中所起作用的程度。2. 即使是低肾素型患者，当实现足够的钠缺失时也会变为肾素依赖型。3. 这些亚组患者之间的主要差异似乎在于他们在标准饮食方案下钠缺失的可变能力。

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Determination of renin-dependency and sodium-dependency in the three renin sub-groups of essential hypertension.原发性高血压三个肾素亚组中肾素依赖性和钠依赖性的测定
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Effect of the angiotensin II antagonist saralasin on plasma aldosterone concentration and on blood pressure before and during sodium depletion in normal subjects.血管紧张素II拮抗剂沙拉新对正常受试者钠耗竭前及钠耗竭期间血浆醛固酮浓度和血压的影响。
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[Saralasin-induced changes of blood pressure, renin and aldosterone in essential and renal hypertension (author's transl)].
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