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Wnts as retrograde signals for axon and growth cone differentiation.

作者信息

Burden S J

机构信息

Molecular Neurobiology Program, Skirball Institute of Biomolecular Medicine, New York University Medical School, New York, New York 10016, USA.

出版信息

Cell. 2000 Mar 3;100(5):495-7. doi: 10.1016/s0092-8674(00)80685-6.

DOI:10.1016/s0092-8674(00)80685-6
PMID:10721986
Abstract
摘要

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1
Wnts as retrograde signals for axon and growth cone differentiation.Wnts作为轴突和生长锥分化的逆行信号。
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2
Axonal remodeling and synaptic differentiation in the cerebellum is regulated by WNT-7a signaling.小脑的轴突重塑和突触分化受WNT-7a信号通路调控。
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Synaptic differentiation: the role of agrin in the formation and maintenance of the neuromuscular junction.突触分化:聚集蛋白在神经肌肉接头形成和维持中的作用
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Synapse-forming axons and recombinant agrin induce microprocess formation on myotubes.形成突触的轴突和重组聚集蛋白聚糖可诱导肌管上形成微突起。
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Growth cone stop signals: inviting to stay or sending away?生长锥停止信号:是留人还是逐客?
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Identification of genomic organisation, sequence variants and analysis of the role of the human dishevelled 1 gene in late onset Alzheimer's disease.人类无序蛋白1基因在晚发性阿尔茨海默病中的基因组组织鉴定、序列变异及作用分析
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Valproate regulates GSK-3-mediated axonal remodeling and synapsin I clustering in developing neurons.丙戊酸盐调节发育中神经元中GSK-3介导的轴突重塑和突触素I聚集。
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WNT-3, expressed by motoneurons, regulates terminal arborization of neurotrophin-3-responsive spinal sensory neurons.由运动神经元表达的WNT-3调节神经营养因子-3反应性脊髓感觉神经元的终末分支。
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eNeuro. 2019 Sep 18;6(5). doi: 10.1523/ENEURO.0026-19.2019. Print 2019 Sep/Oct.

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The Drosophila Wnt, wingless, provides an essential signal for pre- and postsynaptic differentiation.果蝇的Wnt蛋白,即无翅蛋白,为突触前和突触后分化提供重要信号。
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Differentiation of embryonic mesenchymal cells to odontoblast-like cells by overexpression of dentin matrix protein 1.通过牙本质基质蛋白1的过表达使胚胎间充质细胞分化为成牙本质细胞样细胞。
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