Garcia-Vallvé S, Romeu A, Palau J
Department of Biochemistry and Biotechnology, Rovira i Virgili University, Catalonia, Spain.
Mol Biol Evol. 2000 Mar;17(3):352-61. doi: 10.1093/oxfordjournals.molbev.a026315.
By combining analyses of G + C content and patterns of codon usage and constructing phylogenetic trees, we describe the gene transfer of an endoglucanase (celA) from the rumen bacteria Fibrobacter succinogenes to the rumen fungi Orpinomyces joyonii. The strong similarity between different glycosyl hydrolases of rumen fungi and bacteria suggests that most, if not all, of the glycosyl hydrolases of rumen fungi that play an important role in the degradation of cellulose and other plant polysaccharides were acquired by horizontal gene transfer events. This acquisition allows fungi to establish a habitat within a new environmental niche: the rumen of the herbivorous mammals for which cellulose and plant hemicellulose constitute the main raw nutritive substrate.
通过结合对G + C含量和密码子使用模式的分析以及构建系统发育树，我们描述了一种内切葡聚糖酶（celA）从瘤胃细菌琥珀酸纤维杆菌向瘤胃真菌约氏奥尔平霉的基因转移。瘤胃真菌和细菌的不同糖基水解酶之间的高度相似性表明，瘤胃真菌中在纤维素和其他植物多糖降解中起重要作用的大多数（如果不是全部）糖基水解酶是通过水平基因转移事件获得的。这种获得使真菌能够在一个新的环境生态位中建立栖息地：食草哺乳动物的瘤胃，其中纤维素和植物半纤维素构成主要的营养底物原料。
