分娩时硬膜外镇痛的不良反应。

Adverse effects of epidural analgesia in labor.

作者信息

Zimmer E Z, Jakobi P, Itskovitz-Eldor J, Weizman B, Solt I, Glik A, Weiner Z

机构信息

Department of Obstetrics and Gynecology, Rambam Medical Center, Technion-Faculty of Medicine, Haifa, Israel.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2000 Apr;89(2):153-7. doi: 10.1016/s0301-2115(99)00191-8.

DOI:10.1016/s0301-2115(99)00191-8

PMID:10725574

Abstract

OBJECTIVE

To examine the influence of epidural analgesia on labor and delivery in nulliparous and multiparous women.

DESIGN

Data were collected on 847 consecutive parturients with singleton pregnancy and vertex presentation (384 nulliparous and 463 multiparous). The obstetrical and labor characteristics including maternal age, parity, gestational age, previous cesarean section, instrumental delivery, mode and timing of analgesia, mode of delivery, indications for cesarean section or instrumental delivery were analyzed comparing patients who received epidural analgesia with women who received systemic analgesia.

RESULTS

Epidural analgesia was administered in 233 nulliparous and 141 multiparous women. A stepwise logistic regression analysis revealed that epidural analgesia independently affected the rate of non-spontaneous delivery and the duration of the second stage of labor in nulliparous (P=0.0017 and P=0.0036, respectively) and multiparous (P=0.001 and P=0.0081, respectively) women. Epidural analgesia independently affected the duration of labor only in nulliparous women (P=0.0001).

CONCLUSION

Women should be informed that prolongation of labor and increase in nonspontaneous deliveries should be expected when choosing epidural analgesia in labor.

摘要