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在接受腰段硬膜外镇痛的初产妇中,与使用缩宫素加强自然分娩相比,使用缩宫素引产会增加剖宫产率。

Induction of labor with oxytocin increases cesarean section rate as compared with oxytocin for augmentation of spontaneous labor in nulliparous parturients controlled for lumbar epidural analgesia.

作者信息

Kaul Bupesh, Vallejo Manuel C, Ramanathan Sivam, Mandell Gordon, Phelps Amy L, Daftary Ashi R

机构信息

Department of Anesthesiology, Magee-Womens Hospital and the University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.

出版信息

J Clin Anesth. 2004 Sep;16(6):411-4. doi: 10.1016/j.jclinane.2003.11.004.

Abstract

STUDY OBJECTIVES

To study labor outcomes in parturients receiving oxytocin for augmentation or induction of labor, in the presence of labor epidural analgesia.

DESIGN

Retrospective study of data from a continuous quality improvement database.

SETTING

Tertiary-care hospital with more than 8000 deliveries per annum.

MEASUREMENTS AND MAIN RESULTS

Of the 1671 healthy nulliparous women with singleton pregnancies and who requested labor epidural analgesia at our institution, 675 patients received oxytocin during elective induction of labor, whereas 996 patients received oxytocin for augmentation of spontaneous labor. Measured variables were cervical dilatation at time of epidural analgesia request, epidural insertion to 10-cm time, duration of stage 2 of labor, normal spontaneous vaginal delivery rate, cesarean section rate, operative vaginal delivery rate, and baby weight. Women admitted for induction of labor requested epidural analgesia sooner than those who had their labor augmented (p < 0.001). The incidence of cesarean section was higher in the induced group (p = 0.008).

CONCLUSION

Patients who have their labor induced request analgesia sooner and are at a higher risk of cesarean section than are patients who go into labor spontaneously. Any study that purports to assess the effects of epidural analgesia in labor should distinguish between induced and augmented/spontaneous labor.

摘要

研究目的

研究在分娩硬膜外镇痛情况下,接受缩宫素加强宫缩或引产的产妇的分娩结局。

设计

对来自持续质量改进数据库的数据进行回顾性研究。

地点

一家年分娩量超过8000例的三级护理医院。

测量指标及主要结果

在我院1671例要求分娩硬膜外镇痛的单胎妊娠健康初产妇中,675例在择期引产时接受了缩宫素,而996例接受缩宫素用于加强自然宫缩。测量变量包括要求硬膜外镇痛时的宫颈扩张程度、硬膜外穿刺至宫口开全时间、第二产程持续时间、正常自然阴道分娩率、剖宫产率、阴道助产率和出生体重。引产产妇要求硬膜外镇痛的时间比宫缩加强的产妇早(p<0.001)。引产组剖宫产发生率更高(p = 0.008)。

结论

与自然分娩的产妇相比,引产产妇要求镇痛的时间更早,剖宫产风险更高。任何旨在评估硬膜外镇痛对分娩影响的研究都应区分引产和宫缩加强/自然分娩。

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