Fakan F
Cesk Patol. 1976 Aug;12(3):141-6.
A myelosarcoma was diagnosed in the bioptic excision of an eight year old boy's middle ear. An autopsy of this case as well as that of a 47 year old man revealed the presence of tumoriform chloroleukaemia. The histochemical positivity of naphthol AS-D-chloracetate-esterase and NaF-sensitive non-specific esterase showed the simultaneous double differentiation of tumour cells thus serving as evidence of their myelomonocytic nature. The first observation also revealed the presence of atypical eosinophil leucocytes with PAS-positive, naftol AS-D-chloracetate-esterase-negative granules. Both observations brought evidence of the reticular as well as tumour cells showing signs of erythrocytophagia which may have a share in the development of the tumour tissue green coloration.
一名8岁男孩中耳活检切除物被诊断为骨髓肉瘤。对该病例以及一名47岁男性进行尸检,发现存在肿瘤样绿色白血病。萘酚AS-D-氯乙酸酯酶和氟化钠敏感的非特异性酯酶的组织化学阳性显示肿瘤细胞同时出现双重分化,从而证明其具有骨髓单核细胞性质。首次观察还发现存在非典型嗜酸性粒细胞,其颗粒对PAS呈阳性反应、对萘酚AS-D-氯乙酸酯酶呈阴性反应。两项观察均证实网状细胞以及肿瘤细胞有红细胞吞噬迹象,这可能与肿瘤组织绿色着色的形成有关。