Thabet F, Tabarki B, Fehem R, Yacoub M, Selmi H, Essoussi A S
Service de Pédiatrie, Hôpital Farhat Hached, Sousse.
Tunis Med. 1999 Dec;77(12):648-50.
Hemophagocytosis has already been in cases of visceral leishmaniasis and thus may complicate search for diagnosis. We report a case of hemophagocytosis in a 20 month-old boy presenting with fever, hepatosplenomegaly, pancytopenia and coagulopathy. An initial diagnosis of kala-azar was refuted because of absence of biological inflammatory syndrome and negativity of bone-marrow aspiration. Specific serology for visceral leishmaniasis become positive. The boy was given stibogluconate for 21 days; he improves gradually with complete remission.
噬血细胞现象已见于内脏利什曼病病例，因此可能使诊断过程复杂化。我们报告一例20个月大男孩出现噬血细胞现象，伴有发热、肝脾肿大、全血细胞减少和凝血病。由于缺乏生物学炎症综合征且骨髓穿刺结果为阴性，最初的黑热病诊断被推翻。内脏利什曼病的特异性血清学检查呈阳性。该男孩接受了21天的葡萄糖酸锑钠治疗；他逐渐好转并完全缓解。
