Michel G, Simonin G, Perrimond H, Coignet J
Service d'Hématologie Pédiatrique, Hôpital d'Enfants de la Timone, Marseille.
Arch Fr Pediatr. 1988 Jan;45(1):45-6.
We report a case of mononuclear phagocyte system activation observed in a 12 month-old girl presenting with fever, hepatosplenomegaly, pancytopenia, histiocytic hyperplasia with hemophagocytosis in the bone marrow, high triglyceride and low fibrinogen blood levels. This syndrome was associated with visceral leishmaniasis. We conclude that systemic leishmaniasis is a curable cause of disorders characterized by an activation of the mononuclear phagocyte system.
我们报告了一例在一名12个月大女童中观察到的单核吞噬细胞系统激活病例,该女童表现为发热、肝脾肿大、全血细胞减少、骨髓中组织细胞增生伴噬血细胞现象、血液中甘油三酯水平升高和纤维蛋白原水平降低。该综合征与内脏利什曼病相关。我们得出结论,系统性利什曼病是一种可治愈的、以单核吞噬细胞系统激活为特征的疾病病因。