Ranger-Rogez S, Venot C, Denis F
Laboratoire de virologie CHU Dupuytren, Limoges.
Rev Prat. 1999 Dec 15;49(20):2227-31.
Human herpesviruses 6 (HHV-6) and 7 (HHV-7) are world wide T lymphotropic viruses recently discovered. Their transmission is essentially by salivary route. Primary infections which occurred early in infancy, respectively during the first year of life for HHV-6 and in the second or third year for HHV-7, are followed by latency for life. HHV-7 is not actually associated with a disease. HHV-6 primary infection is often asymptomatic, if not it can induce exanthem subitum. HHV-6 reactivation can be symptomatic in immunodeficient subjects. The role of HHV-6 in the arising of lymphoproliferative or auto-immune diseases, discussed for a long time, is still to elucidate. HHV-6 infection is diagnosed by serodiagnosis in case of primary infection, but in the great number of cases, it would be realized by polymerases chain reaction.
人类疱疹病毒6型（HHV-6）和7型（HHV-7）是最近发现的全球嗜T淋巴细胞病毒。它们主要通过唾液途径传播。原发性感染分别发生在婴儿早期，HHV-6在出生后第一年，HHV-7在第二年或第三年，随后终身潜伏。HHV-7实际上与疾病无关。HHV-6原发性感染通常无症状，否则可诱发幼儿急疹。HHV-6再激活在免疫缺陷患者中可能有症状。长期以来一直在讨论HHV-6在淋巴增殖性或自身免疫性疾病发生中的作用，仍有待阐明。原发性感染时通过血清学诊断HHV-6感染，但在大多数情况下，将通过聚合酶链反应来实现。
