Smith R A, Mettlin C J, Davis K J, Eyre H
American Cancer Society, Atlanta, GA, USA.
CA Cancer J Clin. 2000 Jan-Feb;50(1):34-49. doi: 10.3322/canjclin.50.1.34.
This issue of CA inaugurates a yearly report on American Cancer Society guidelines for early detection of cancer in asymptomatic individuals. The current recommendations, which reflect almost 20 years of updates, cover screening recommendations for breast, colorectal, prostate, and cervical cancers, as well as for other cancers, depending on patient age, history, environmental and/or occupational exposures, etc. A key concept for both the general public and health providers is the distinction between public health recommendations regarding screening and decisions about early detection tests that might be undertaken on an individual basis. Although it is likely that current screening protocols will be supplanted by newer technologies, such as genetic and molecular markers of risk and disease, greater utilization of the technologies at hand will improve efforts toward establishing an organized and systematic approach to early cancer detection.
本期《CA》杂志开创了一份关于美国癌症协会针对无症状个体癌症早期检测指南的年度报告。当前的建议反映了近20年的更新内容,涵盖了乳腺癌、结直肠癌、前列腺癌和宫颈癌以及其他癌症的筛查建议,具体取决于患者年龄、病史、环境和/或职业暴露等因素。对于普通公众和医疗服务提供者而言,一个关键概念是关于筛查的公共卫生建议与可能针对个体进行的早期检测测试决策之间的区别。尽管当前的筛查方案很可能会被更新的技术所取代,比如风险和疾病的基因及分子标志物,但更多地利用现有技术将有助于改进建立有组织、系统的早期癌症检测方法的工作。