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巨乳缩小术标本的组织病理学评估以检测隐匿性乳腺癌:来自伊朗南部的报告

Histopathological evaluation of reduction mammaplasty specimens to detect occult breast cancer: a report from southern iran.

作者信息

Rajabian Mohammad Hossain, Vijayananda Kumar Perikala

机构信息

Department of Plastic, Reconstructive and Aesthetic Surgery, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Department of Pathology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

World J Plast Surg. 2012 Jul;1(2):71-5.

PMID:25734047
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4344533/
Abstract

BACKGROUND

Reduction mammaplasty (RM) is among the commonly performed procedures by plastic surgeons. Occult breast cancers are rarely detected in these specimens. The purpose of the study was to describe histopathological evaluation of reduction mammaplasty specimens to detect occult breast cancer in Southern Iran.

METHODS

The histological diagnosis of 350 RM specimens from 175 patients to detect occult breast cancer was evaluated retrospectively. This study determines the incidence of breast cancer too.

RESULTS

Microscopic examination revealed that 233 specimens had no pathological changes, 106 showed evidences of fibrocystic disease, 2 were diagnosed as fibroadenoma, 4 were diagnosed as adenosis and one was diagnosed as a phylloides tumor. Furthermore, 4 specimens were diagnosed as carcinomas; 2 as medullary carcinoma and 2 as intraductal carcinoma. Four occult carcinomas were detected in young, unmarried women.

CONCLUSION

Thorough gross and microscopic examination helped to detect these occult carcinomas and also helped in planning futuretreatments. We consider a thorough gross examination and sampling of mammaplasty specimens to be mandatory.

摘要

背景

缩乳术(RM)是整形外科医生常做的手术之一。在这些手术切除的标本中很少能检测出隐匿性乳腺癌。本研究的目的是描述对伊朗南部缩乳术标本进行组织病理学评估以检测隐匿性乳腺癌的情况。

方法

回顾性评估了175例患者的350份缩乳术标本的组织学诊断以检测隐匿性乳腺癌。本研究还确定了乳腺癌的发病率。

结果

显微镜检查显示,233份标本无病理变化,106份有纤维囊性疾病的迹象,2份被诊断为纤维腺瘤,4份被诊断为腺病,1份被诊断为叶状肿瘤。此外,4份标本被诊断为癌;2份为髓样癌,2份为导管内癌。在年轻未婚女性中检测到4例隐匿性癌。

结论

全面的大体和显微镜检查有助于检测这些隐匿性癌,也有助于规划未来的治疗。我们认为对缩乳术标本进行全面的大体检查和取样是必不可少的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e95/4344533/f1295e1e2e30/wjps-1-071-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e95/4344533/f1295e1e2e30/wjps-1-071-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e95/4344533/f1295e1e2e30/wjps-1-071-g001.jpg

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本文引用的文献

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Incidence of breast cancer in fars province, southern iran: a hospital-based study.伊朗南部法尔斯省乳腺癌发病率:一项基于医院的研究。
World J Plast Surg. 2012 Jan;1(1):16-21.
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Does histopathological examination of breast reduction specimens affect patient management and clinical follow up?对缩乳标本进行组织病理学检查会影响患者的治疗管理和临床随访吗?
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Suspicious findings in reduction mammaplasty specimens: review of 182 consecutive patients.缩乳术标本中的可疑发现:对182例连续患者的回顾
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Pathologic findings in reduction mammaplasty specimens.缩乳术标本的病理检查结果。
Am J Clin Pathol. 2003 Sep;120(3):377-80. doi: 10.1309/4kd652hn739xtlm3.