Grimshaw J, Campbell M, Eccles M, Steen N
Health Services Research Unit, University of Aberdeen, UK.
Fam Pract. 2000 Feb;17 Suppl 1:S11-6. doi: 10.1093/fampra/17.suppl_1.s11.
The choice of study design for guideline implementation studies will determine the confidence with which the observed effects can be attributed to the interventions under study. In general, cluster randomized trials, of which there are different types, provide the most robust design. However, the use of these designs has implications for the power, conduct and analysis of studies. Wherever possible, designs allowing head-to-head comparisons, which incorporate baseline measures of performance, should be used.
指南实施研究的研究设计选择将决定观察到的效果可归因于所研究干预措施的可信度。一般来说，有不同类型的整群随机试验提供了最可靠的设计。然而，这些设计的使用对研究的效能、实施和分析有影响。只要有可能，就应使用允许进行直接比较且纳入了绩效基线测量的设计。
