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对前列腺癌患者身体功能的简要评估。

A brief assessment of physical functioning for prostate cancer patients.

作者信息

Lai Jin-Shei, Bode Rita, Wee Hwee-Lin, Eton David, Cella David

机构信息

Department of Medical Social Sciences.

出版信息

Patient Relat Outcome Meas. 2010 Jul;1:51-6. doi: 10.2147/prom.s10658. Epub 2010 Jun 18.

DOI:10.2147/prom.s10658
PMID:22915952
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3417897/
Abstract

We aimed to validate a more rapid, yet reliable means of assessing physical function (PF) for patients with prostate cancer. The sample included 128 prostate cancer patients recruited from urology and general oncology clinics at two Chicago-area hospitals. The main outcome measures were: A 36-item PF item bank that included a 5-item short form (BriefPF) and the 10-item PF subscale (PF-10) from the Medical Outcomes Study SF-36. Validity, information function, and relative precision (calculated using Rasch analysis and raw scores) of the BriefPF were compared to the PF-10 and the full PF item bank. We found that the BriefPF and PF-10 were strongly correlated (r = 0.85) with the PF bank, and all three scales differentiated patients according to performance status (F(PF bank)(2,124) = 32.51 P < 0.001, F(PF-10)(2,121) = 27.35 P < 0.001, F(BriefPF) (2,123) = 38.40 P < 0.001). BriefPF has excellent precision relative to the PF-10 in measuring patients with different performance status levels. The Rasch-based information function indicated that the BriefPF was more informative than PF-10 in measuring moderate to higher functioning patients. Hence, the BriefPF offers a parsimonious and precise measure of PF for use among men with prostate cancer, and may aid in the timely inclusion of patient-reported outcomes in treatment decision-making.

摘要

我们旨在验证一种更快速且可靠的方法,用于评估前列腺癌患者的身体功能(PF)。样本包括从芝加哥地区两家医院的泌尿外科和普通肿瘤诊所招募的128名前列腺癌患者。主要结局指标为:一个包含36个项目的PF题库,其中包括一个5项简短形式(BriefPF)以及医学结局研究简表36(SF-36)中的10项PF子量表(PF-10)。将BriefPF的效度、信息功能和相对精度(使用拉施分析和原始分数计算)与PF-10和完整的PF题库进行比较。我们发现BriefPF和PF-10与PF题库高度相关(r = 0.85),并且所有三个量表都根据患者的表现状态区分了患者(F(PF题库)(2,124)= 32.51,P < 0.001;F(PF-10)(2,121)= 27.35,P < 0.001;F(BriefPF)(2,123)= 38.40,P < 0.001)。在测量不同表现状态水平的患者时,BriefPF相对于PF-10具有出色的精度。基于拉施的信息功能表明,在测量中度至较高功能的患者时,BriefPF比PF-10提供的信息更多。因此,BriefPF为前列腺癌男性患者提供了一种简洁而精确的PF测量方法,可能有助于在治疗决策中及时纳入患者报告的结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e590/3417897/8fe621cfae95/prom-1-051f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e590/3417897/8fe621cfae95/prom-1-051f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e590/3417897/8fe621cfae95/prom-1-051f1.jpg

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本文引用的文献

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Falls and physical performance deficits in older patients with prostate cancer undergoing androgen deprivation therapy.接受雄激素剥夺治疗的老年前列腺癌患者的跌倒及身体功能缺陷
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Physical function changes in prostate cancer patients on androgen deprivation therapy: a 2-year prospective study.接受雄激素剥夺治疗的前列腺癌患者的身体功能变化:一项为期2年的前瞻性研究。
Urology. 2008 Apr;71(4):735-9. doi: 10.1016/j.urology.2007.09.018. Epub 2008 Feb 15.
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Expansion of a physical function item bank and development of an abbreviated form for clinical research.
物理功能条目库的扩展及临床研究简表的编制
J Appl Meas. 2006;7(1):1-15.
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Time trends in clinical risk stratification for prostate cancer: implications for outcomes (data from CaPSURE).前列腺癌临床风险分层的时间趋势:对结局的影响(来自CaPSURE的数据)
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Developing an initial physical function item bank from existing sources.从现有资源中开发初始身体功能项目库。
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Issues in the development of an item bank.题库开发中的问题。
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Health related quality of life in men with prostate cancer.前列腺癌男性患者的健康相关生活质量
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Assessing quality of life in research and clinical practice.评估研究与临床实践中的生活质量。
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Prostate cancer and health-related quality of life: a review of the literature.前列腺癌与健康相关生活质量:文献综述
Psychooncology. 2002 Jul-Aug;11(4):307-26. doi: 10.1002/pon.572.
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Quality of life following localized prostate cancer treated initially with androgen deprivation therapy or no therapy.初始接受雄激素剥夺治疗或未接受治疗的局限性前列腺癌患者的生活质量。
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