Bolz U, Körner W, Hagenmaier H
Institute of Organic Chemistry, University of Tübingen, Germany.
Chemosphere. 2000 May-Jun;40(9-11):929-35. doi: 10.1016/s0045-6535(99)00335-5.
A simple and sensitive GC/MS method for the quantitative determination of the estrogenic phenolic compounds 4-nonylphenol, 4-t-octylphenol, bisphenol A, 3-t-butyl-4-hydroxyanisole, 2-t-butyl-4-methylphenol, 4-hydroxybiphenyl, 2-hydroxybiphenyl, 4-chloro-3-methylphenol, and 4-chloro-2-methylphenol in aquatic samples was developed. The method for assessing their occurrence in sewage, surface and drinking waters consists of solid phase extraction (SPE) using a polystyrene copolymer phase. After methylation of the extract HRGC/LRMS analysis was possible without any clean up, even in raw sewage samples. Limits of detection and determination were between <0.01 and 0.05 ng/l and 0.01 and 0.05 ng/l, respectively. Recoveries were above 70% with exception of 3-t-butyl-4-hydroxyanisole.
建立了一种简单灵敏的气相色谱/质谱法，用于定量测定水生样品中的雌激素酚类化合物4-壬基酚、4-叔辛基酚、双酚A、3-叔丁基-4-羟基茴香醚、2-叔丁基-4-甲基苯酚、4-羟基联苯、2-羟基联苯、4-氯-3-甲基苯酚和4-氯-2-甲基苯酚。评估这些化合物在污水、地表水和饮用水中存在情况的方法包括使用聚苯乙烯共聚物相进行固相萃取（SPE）。提取物甲基化后，即使是未经处理的污水样品，也无需任何净化即可进行高分辨气相色谱/低分辨质谱分析。检测限和定量限分别在<0.01至0.05 ng/L和0.01至0.05 ng/L之间。除3-叔丁基-4-羟基茴香醚外，回收率均高于70%。
