Cohen-Solal A, Desnos M, Delahaye F, Emeriau J P, Hanania G
Eur Heart J. 2000 May;21(9):763-9. doi: 10.1053/euhj.1999.1762.
Rationale The epidemiology of heart failure and patient management procedures may vary from one country to another. This study was designed to analyse the spectrum of patients hospitalized in France for heart failure. Patients and Methods A registry involving 120 departments (cardiology, general medicine and geriatrics) and 1058 patients.Results The patients' median age was 76 years, and the male/female ratio was 55/45. Echocardiography was performed in 77% of the cases: the left ventricular ejection fraction was <30% in 22%, between 30 and 40% in 25% and greater than 40% in 53%. Angiotensin-converting enzyme (ACE) inhibitors were prescribed to, respectively, 78% and 63% of patients with ejection fractions above and below 40%. Conclusion In France, patients hospitalized for heart failure tend to be old and are often women; about one in two have relatively preserved left ventricular systolic function. ACE inhibitor prescription seems to be more frequent than currently reported. This survey confirms the clear gap between the populations in clinical trials and those in routine clinical practice.
理论依据 心力衰竭的流行病学及患者管理程序可能因国家而异。本研究旨在分析法国因心力衰竭住院的患者情况。
患者与方法 一项登记研究涉及120个科室（心脏病学、普通内科和老年医学科）及1058名患者。
结果 患者的中位年龄为76岁，男女比例为55/45。77%的病例进行了超声心动图检查：左心室射血分数<30%的占22%，30%至40%的占25%，大于40%的占53%。射血分数高于和低于40%的患者中，分别有78%和63%的患者使用了血管紧张素转换酶（ACE）抑制剂。
结论 在法国，因心力衰竭住院的患者往往年龄较大且女性居多；约二分之一的患者左心室收缩功能相对保留。ACE抑制剂的处方使用率似乎比目前报道的更高。这项调查证实了临床试验人群与常规临床实践人群之间存在明显差距。
