[皮肤受累对口腔恶性肿瘤的预后影响]

[Prognostic influence of cutaneous involvement in malignant tumors of the oral cavity].

作者信息

Tankéré F, Camproux A, Barry B, Guedon C, Depondt J, Gehanno P

机构信息

Service d'O.R.L. et de chirurgie cervico-faciale, Hôpital Bichat Claude-Bernard, Paris, France.

出版信息

Ann Otolaryngol Chir Cervicofac. 2000 Mar;117(2):85-90.

PMID:10739997

Abstract

The aim of this study was to assess the prognostic influence of cutaneous involvement in T4 squamous cell carcinoma of the oral cavity. The population was a homogeneous group of 137 patients. Cutaneous tumor localizations were observed in 20 of them. Surgery and radiotherapy were given in 103 cases and salvage surgery was performed in 34. Local control at 5 years was achieved in 68.5 % of the patients. Carcinologic failure rate was 55 % and 27.3 % in patients with and without cutaneous involvement respectively (p =0. 013). 5-year survivor rate was also correlated with cutaneous involvement: 10 % versus 32.2 % (p <0.0001).

摘要

本研究的目的是评估口腔T4期鳞状细胞癌皮肤受累的预后影响。研究人群为137例同质患者。其中20例观察到皮肤肿瘤定位。103例患者接受了手术和放疗，34例进行了挽救性手术。5年局部控制率在68.5%的患者中实现。有皮肤受累和无皮肤受累患者的肿瘤学失败率分别为55%和27.3%（p = 0.013）。5年生存率也与皮肤受累相关：分别为10%和32.2%（p < 0.0001）。