Cole C R, Foody J M, Blackstone E H, Lauer M S
Department of Cardiology, Cleveland Clinic Foundation, Ohio 44195, USA.
Ann Intern Med. 2000 Apr 4;132(7):552-5. doi: 10.7326/0003-4819-132-7-200004040-00007.
Abnormal heart rate recovery after symptom-limited exercise predicts death. It is unknown whether this is also true among patients undergoing submaximal testing.
To test the prognostic implications of heart rate recovery in cardiovascularly healthy adults undergoing submaximal exercise testing.
Population-based cohort study.
10 primary care sites.
5234 adults without evidence of cardiovascular disease who were enrolled in the Lipid Research Clinics Prevalence Study.
Heart rate recovery was defined as the change from peak heart rate to that measured 2 minutes later (heart rate recovery was defined as < or =42 beats/min).
During 12 years of follow-up, 312 participants died. Abnormal heart rate recovery predicted death (relative risk, 2.58 [CI, 2.06 to 3.20]). After adjustment for standard risk factors, fitness, and resting and exercise heart rates, abnormal heart rate recovery remained predictive (adjusted relative risk, 1.55 [CI, 1.22 to 1.98]) (P<0.001).
Even after submaximal exercise, abnormal heart rate recovery predicts death.
症状受限运动后心率恢复异常可预测死亡。在进行次极量测试的患者中情况是否如此尚不清楚。
检验次极量运动测试中心率恢复对心血管健康成年人的预后意义。
基于人群的队列研究。
10个初级保健机构。
5234名无心血管疾病证据的成年人，他们参与了脂质研究临床患病率研究。
心率恢复定义为从最高心率到2分钟后测量心率的变化（心率恢复定义为≤42次/分钟）。
在12年的随访期间，312名参与者死亡。心率恢复异常可预测死亡（相对风险，2.58[可信区间，2.06至3.20]）。在调整标准风险因素、健康状况以及静息和运动心率后，心率恢复异常仍具有预测性（调整后相对风险，1.55[可信区间，1.22至1.98]）（P<0.001）。
即使在次极量运动后，心率恢复异常也可预测死亡。
