Nakao F S, Brant C Q, Stanich P, Ferrari Júnior A P
Gastroenterology Department, Federal University of São Paulo Medical School, UNIFESP, Brasil.
Arq Gastroenterol. 1999 Jul-Sep;36(3):148-53.
With increased use of percutaneous endoscopic gastrostomy, it became clear that neurologically impaired patients might benefit from its use. From August 1996 to July 1997, we performed 19 percutaneous endoscopic gastrostomies in patients with neurological sequelae, who were incapable to maintain their nutritional status by oral ingestion or had repeated episodes of aspiration. Sixteen patients were followed prospectively, from 30 days to 11 months (median: 6.4 months). Average weight (38.2 kg to 44.8 kg), BMI (14.8 kg/m2 to 17.8 kg/m2), weight/height ratio (23.5 kg/cm to 28 kg/cm), mid-upper arm circumference (19.4 cm to 21.6 cm) and triceps skinfold thickness (10.3 mm to 12.6 mm) were significantly increased (P < 0.01). Before percutaneous endoscopic gastrostomy, there were 10 (10/16, 62.5%) patients with grade III thinness. In this group, 3/10 patients (30%) showed improvement to grade I (two individuals) and II (one patient). All but five patients (68.75%) were below the fifth percentile of normal distribution for mid-upper arm circumference. One patient (6.2%) showed improvement of her status (between 25th and 50th percentiles). Four patients (25%) started the follow-up below the fifth percentile for normal distribution of triceps skinfold thickness, and showed no improvement. There were no early complications secondary the procedure. Late complications included granulation tissue on ostomy site (18.8%) and ostomy infection (6.2%). Statistical analysis showed significant improvement of anthropometric data. Percutaneous endoscopic gastrostomy is a simple, highly successful and safe procedure, when performed in neurologically impaired patients. It is efficient as a long-term enteral feeding method.
随着经皮内镜下胃造口术(PEG)使用的增加,很明显神经功能受损的患者可能会从该手术中获益。1996年8月至1997年7月,我们对16例有神经功能后遗症、无法通过口服摄入维持营养状况或反复发生误吸的患者进行了19次经皮内镜下胃造口术。16例患者进行了前瞻性随访,时间从30天至11个月(中位数:6.4个月)。平均体重(从38.2千克增至44.8千克)、体重指数(从14.8千克/平方米增至17.8千克/平方米)、体重/身高比(从23.5千克/厘米增至28千克/厘米)、上臂中部周长(从19.4厘米增至21.6厘米)和肱三头肌皮褶厚度(从10.3毫米增至12.6毫米)均显著增加(P<0.01)。在进行经皮内镜下胃造口术之前,有10例(10/16,62.5%)患者为Ⅲ度消瘦。在这组患者中,3/10例患者(30%)改善为Ⅰ度(2例)和Ⅱ度(1例)。除5例患者(68.75%)外,所有患者的上臂中部周长均低于正常分布的第五百分位数。1例患者(6.2%)的状况有所改善(在第25至50百分位数之间)。4例患者(25%)在肱三头肌皮褶厚度正常分布的第五百分位数以下开始随访,且无改善。该手术无早期并发症。晚期并发症包括造口部位肉芽组织(18.8%)和造口感染(6.2%)。统计分析显示人体测量数据有显著改善。经皮内镜下胃造口术在神经功能受损患者中实施时是一种简单、成功率高且安全的手术。作为一种长期肠内喂养方法,它是有效的。