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阿尔茨海默病中短时间间隔的估计

Estimation of short temporal intervals in Alzheimer's disease.

作者信息

Carrasco M C, Guillem M J, Redolat R

机构信息

Facultad de Psicología, Universitat de València, Spain.

出版信息

Exp Aging Res. 2000 Apr-Jun;26(2):139-51. doi: 10.1080/036107300243605.

DOI:10.1080/036107300243605
PMID:10755220
Abstract

This study investigated the estimation of short temporal intervals in Alzheimer's disease (AD). Eight patients with dementia of the Alzheimer type, and eight age-matched controls were evaluated in a time-estimation task. The task consisted in the production of three short empty intervals (5, 10, and 25 s). Results indicated that AD patients show deficits both in the accuracy and precision of time judgments: in the three intervals evaluated, the magnitude of absolute error and the variability in time judgments were significantly greater in AD patients than healthy respondents (p < .01). These findings are discussed taking into account the contribution of attentional processes during the performance of temporal tasks. It is concluded that the estimation of short temporal intervals could be useful as an objective indicator of cognitive decline in AD.

摘要

本研究调查了阿尔茨海默病(AD)患者对短时间间隔的估计能力。对8名阿尔茨海默型痴呆患者和8名年龄匹配的对照者进行了时间估计任务评估。该任务包括产生三个短的空时间间隔(5秒、10秒和25秒)。结果表明,AD患者在时间判断的准确性和精确性方面均表现出缺陷:在评估的三个时间间隔中,AD患者的绝对误差幅度和时间判断的变异性显著大于健康受试者(p < .01)。结合执行时间任务期间注意力过程的作用对这些发现进行了讨论。得出的结论是,短时间间隔的估计可用作AD患者认知衰退的客观指标。

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