Târcoveanu E, Pleşa C, Chifan M, Daniil C, Niculescu D, Bârza M, Crumpei F, Florea N, Balan G, Volovăţ C, Moisi L, Epure O
Clinica a I-a Chirurgicală, Facultatea de Medicină, Universitatea de Medicină şi Farmacie Gr. T. Popa, Iaşi.
Rev Med Chir Soc Med Nat Iasi. 1999 Jan-Jun;103(1-2):151-60.
During the period 1989-1998, 27 patients with primary proximal bile duct cancer were treated (17 females and 10 males with a mean age of 61 years). The main presenting symptoms were: jaundice (96.2%), itching (92.5%), weight loss (74%) and atypical pain (33.3%). All the patients underwent ultrasound (US) examination, 7 patients endoscopic retrograde cholangiopancreatography (ERCP) and 4 patients computed tomography (CT) examination. US examination revealed the tumor in 51% cases; most frequently a dilatation of the intrahepatic bile ducts was diagnosed with all methods. 8 patients underwent resection of the tumor and one a biliary-enteric anastomosis, in 15 cases a stent was inserted. In 3 cases the extension of the malignancy did not allowed any procedure. Three patients died during immediate postoperative period (mortality 11.2%). The mean survival was 13 months after stenting and 22 months after resection of the tumor. The authors recommended an aggressive surgical therapy for Klatskin tumors.
在1989年至1998年期间，对27例原发性近端胆管癌患者进行了治疗（17例女性和10例男性，平均年龄61岁）。主要临床表现为：黄疸（96.2%）、瘙痒（92.5%）、体重减轻（74%）和非典型疼痛（33.3%）。所有患者均接受了超声（US）检查，7例患者接受了内镜逆行胰胆管造影（ERCP）检查，4例患者接受了计算机断层扫描（CT）检查。超声检查在51%的病例中发现了肿瘤；所有方法最常诊断出肝内胆管扩张。8例患者接受了肿瘤切除术，1例进行了胆肠吻合术，15例插入了支架。3例患者因恶性肿瘤扩散无法进行任何手术。3例患者在术后近期死亡（死亡率11.2%）。支架置入后的平均生存期为13个月，肿瘤切除后的平均生存期为22个月。作者建议对Klatskin肿瘤采取积极的手术治疗。
