Kobayashi J, Sekiguchi M, Shigemori H, Ohsaki A
Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
J Nat Prod. 2000 Mar;63(3):375-7. doi: 10.1021/np9905261.
A new seco-labdane-type diterpenoid, chapecoderin A (1), and two new rearranged labdane-type diterpenoids, chapecoderins B (2) and C (3), were isolated from the leaves of the Brazilian medicinal plant Echinodorus macrophyllus ("Chapéu-de-couro"), and their structures and relative stereochemistry were elucidated by spectroscopic data. Chapecoderins A-C (1-3) possess in common an alpha,beta-unsaturated gamma-lactone ring in the side chain.
