Pham N B, Butler M S, Quinn R J
Queensland Pharmaceutical Research Institute, Griffith University, Brisbane, Australia 4111.
J Nat Prod. 2000 Mar;63(3):393-5. doi: 10.1021/np990335y.
Psammaplin A 11'-sulfate (3) and bisaprasin 11'-sulfate (4) have been isolated from the marine sponge Aplysinella rhax, along with the known psammaplin A (1). Their structures were determined on the basis of their spectroscopic data. Compounds 1 and 3 inhibited [(3)H]1,3-dipropyl-8-cyclopentylxanthine binding to rat-brain adenosine A(1) receptors.
从海洋海绵Aplysinella rhax中分离出了沙马普林A 11'-硫酸盐（3）和双阿普瑞辛11'-硫酸盐（4），以及已知的沙马普林A（1）。根据它们的光谱数据确定了它们的结构。化合物1和3抑制了[(3)H]1,3 - 二丙基 - 8 - 环戊基黄嘌呤与大鼠脑腺苷A(1)受体的结合。
