Weiner M F, Tractenberg R, Teri L, Logsdon R, Thomas R G, Gamst A, Thal L J
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75235-9070, USA.
J Psychiatr Res. 2000 Mar-Apr;34(2):163-7. doi: 10.1016/s0022-3956(99)00042-4.
In the course of a four-month study of interventions for behavioral disturbances in Alzheimer's disease (AD) patients, the following assessment instruments were examined for validity: the clinical global impression of change (CGIC), Cohen-Mansfield agitation inventory (CMAI); CERAD behavioral rating scale for dementia (BRSD), revised memory and behavioral problems checklist (RMBPC) and the agitated behavior in dementia scale (ABID). The four specific behavioral/agitation scales had excellent cross-sectional and longitudinal correlations with each other, suggesting high validity, but changes as indicated by CGIC scores did not correlate well with change scores on the other instruments. We conclude that specific behavioral instruments are preferable to the more general CGIC for detecting and quantifying behavioral disturbances in AD patients.
在一项针对阿尔茨海默病（AD）患者行为障碍干预措施的为期四个月的研究过程中，对以下评估工具的有效性进行了检验：临床总体印象变化量表（CGIC）、科恩-曼斯菲尔德激越量表（CMAI）、痴呆的CERAD行为评定量表（BRSD）、修订版记忆与行为问题清单（RMBPC）以及痴呆激越行为量表（ABID）。这四个特定的行为/激越量表相互之间具有出色的横断面和纵向相关性，表明效度较高，但CGIC评分所显示的变化与其他工具的变化评分相关性不佳。我们得出结论，在检测和量化AD患者的行为障碍方面，特定的行为工具比更通用的CGIC更可取。
