Krum J G, Ensign S A
Department of Chemistry, Utah State University, Logan, Utah 84322-0300, USA.
J Bacteriol. 2000 May;182(9):2629-34. doi: 10.1128/JB.182.9.2629-2634.2000.
Coenzyme M (CoM) (2-mercaptoethanesulfonic acid) biosynthesis is shown to be coordinately regulated with the expression of the enzymes of alkene and epoxide metabolism in the propylene-oxidizing bacteria Xanthobacter strain Py2 and Rhodococcus rhodochrous strain B276. These results provide the first evidence for the involvement of CoM in propylene metabolism by R. rhodochrous and demonstrate for the first time the inducible nature of eubacterial CoM biosynthesis.
辅酶M(CoM)(2-巯基乙烷磺酸)的生物合成与丙烯氧化细菌黄杆菌属Py2菌株和红球菌属红平红球菌B276菌株中烯烃和环氧化物代谢酶的表达协同调控。这些结果首次证明了CoM参与红平红球菌的丙烯代谢,并首次证明了真细菌CoM生物合成的可诱导性。