Gotoff S P
Department of Pediatrics, Rush-Presbyterian St. Luke's Medical Center, Chicago, Illinois 60612-3833, USA.
Curr Opin Pediatr. 2000 Apr;12(2):105-10. doi: 10.1097/00008480-200004000-00003.
The evolution of the guidelines for selective intrapartum chemoprophylaxis (SIC) of group B streptococcal early-onset disease is reviewed here. To assess the benefits of the risk-based and culture-based strategies for prevention, observational studies since 1996 are summarized. The effect of chorioamnionitis on group B streptococcal early-onset disease, despite SIC, is emphasized. Optimal management remains controversial, and alternative strategies for the selection of women for chemoprophylaxis and for the management of infants are discussed.
本文回顾了B族链球菌早发型疾病选择性产时化学预防（SIC）指南的演变。为评估基于风险和基于培养的预防策略的益处，总结了自1996年以来的观察性研究。强调了尽管进行了SIC，但绒毛膜羊膜炎对B族链球菌早发型疾病的影响。最佳管理仍存在争议，并讨论了选择进行化学预防的女性以及管理婴儿的替代策略。
