Baker C J
Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.
Clin Perinatol. 1997 Mar;24(1):59-70.
Group B streptococcal disease remains a prominent cause of infectious morbidity in pregnant women and their infants. This article highlights recent developments that are relevant for obstetricians, perinatologists, and neonatologists caring for patients with group B streptococcal disease. The morbidity of group B streptococcal infections in pregnancy and the proposed association of colonization with adverse pregnancy outcome is discussed, as is the emergence of serotype V and the impact of late, late-onset disease for infants. Finally, the recently proposed guidelines for intrapartum chemoprophylaxis are summarized. Implementation of the guidelines should have substantial impact on reduction of early-onset group B streptococcal infections in infancy.
B族链球菌病仍然是孕妇及其婴儿感染性发病的一个主要原因。本文重点介绍了与照顾B族链球菌病患者的产科医生、围产医学专家和新生儿科医生相关的最新进展。文中讨论了妊娠期B族链球菌感染的发病率以及所提出的定植与不良妊娠结局之间的关联，还讨论了V型血清型的出现以及晚期、晚发型疾病对婴儿的影响。最后，总结了最近提出的产时化学预防指南。实施这些指南应对降低婴儿早发型B族链球菌感染产生重大影响。
