Harichaux P, Hary L, Lienard J
Ann Anesthesiol Fr. 1976;17(2):145-56.
This is a very precise study of the mechanisms which intervene in bronchial motility. It is apparent that the most important recent acquisitions in the realm of bronchial mediators, over these last 10 years remains: the demonstration in the animal and in man of the duality between adrenergic bronchoconstriction of alpha nature and adrenergic bronchoconstriction of beta-2 nature, the duality of the effects of prostaglandins (PGF2 alpha broncho-constrictive, and PGE2 bronchodilator), and the role of cyclic AMP at the junction of the action of numerous substances which are active on the bronchial musculature.
这是一项关于干预支气管运动机制的非常精确的研究。很明显,在过去10年里,支气管介质领域最重要的最新进展仍然是:在动物和人类身上证实了α型肾上腺素能支气管收缩和β - 2型肾上腺素能支气管收缩之间的二元性、前列腺素作用的二元性(PGF2α引起支气管收缩,PGE2引起支气管扩张)以及环磷酸腺苷在众多对支气管肌肉组织有活性的物质作用中的连接作用。