Lightfoot N, Conlon M, Kreiger N, Bissett R, Desai M, Warde P, Prichard H M
Epidemiology Research Unit, Northeastern Ontario Regional Cancer Centre (NEORCC), Sudbury, Canada.
Eur Urol. 2000 May;37(5):521-7. doi: 10.1159/000020188.
To determine the impact of non-invasive imaging, specifically ultrasound imaging and computed tomography, on the incidental detection of renal cell carcinoma during two consecutive time periods, one prior and one subsequent to the acquisition of imaging equipment.
All located patient charts (83% of 207) of renal cell carcinoma cases (n = 172) were reviewed, and categorized by presentation method as 'incidental' or 'nonincidental' cases, based on defined criteria. Clinical information was recorded, cases were staged, and survival estimates were calculated.
More than a third of the 172 cases were categorized as incidentally detected, most of which (82.5%) were detected during the latter time period. Either ultrasound or CT imaging was credited with detecting over 80% of the incidentally detected tumors.
Ultrasound and CT imaging have contributed to the incidental detection of renal cell carcinomas during the two time periods. Stage significantly predicted survival (p<0.001) in a Cox proportional hazard model that also controlled for presentation, sex, and age.
确定非侵入性成像，特别是超声成像和计算机断层扫描，在两个连续时间段内对肾细胞癌偶然发现的影响，一个时间段在购置成像设备之前，另一个时间段在购置成像设备之后。
回顾了所有已定位的肾细胞癌病例（n = 172）的患者病历（占207例的83%），并根据既定标准按呈现方式分为“偶然”或“非偶然”病例。记录临床信息，对病例进行分期，并计算生存估计值。
172例病例中超过三分之一被归类为偶然发现，其中大部分（82.5%）是在后面的时间段发现的。超声或CT成像检测出超过80%的偶然发现的肿瘤。
超声和CT成像在这两个时间段有助于偶然发现肾细胞癌。在一个同时控制了呈现方式、性别和年龄的Cox比例风险模型中，分期显著预测了生存率（p<0.001）。
