Lopez P, Perez Ureña M T, Espinosa M, Portoles A
Zentralbl Bakteriol Naturwiss. 1978;133(7-8):690-7. doi: 10.1016/s0323-6056(78)80075-5.
Bacillus subtilis, growing in Bott and Wilson's medium, develops two peaks of competence in batch cultures. The first maximum developed during the exponential growth phase and it has been studied comparatively with the competence level reached in continuous culture at Dt = 2.5 h. In both cases, 100 microgram/ml of arginine inhibited competence. Continuous cultures treated with arginine recovered competence specifically after the addition of Mn2+. In addition, a reduction in the synthesis of aconitase and fumarase was observed in the arginine-inhibited continuous cultures.
枯草芽孢杆菌在博特和威尔逊培养基中生长时，在分批培养中会出现两个感受态高峰。第一个高峰出现在指数生长期，并且已经与在稀释率（Dt）= 2.5小时的连续培养中达到的感受态水平进行了比较研究。在这两种情况下，100微克/毫升的精氨酸都会抑制感受态。用精氨酸处理过的连续培养物在添加Mn2+后特异性地恢复了感受态。此外，在精氨酸抑制的连续培养物中观察到乌头酸酶和延胡索酸酶的合成减少。
