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脓毒症和感染性休克中的代谢紊乱

Metabolic derangements in sepsis and septic shock.

作者信息

Mizock B A

机构信息

Department of Medicine, Cook County Hospital, Chicago, Illinois, USA.

出版信息

Crit Care Clin. 2000 Apr;16(2):319-36, vii. doi: 10.1016/s0749-0704(05)70112-3.

DOI:10.1016/s0749-0704(05)70112-3
PMID:10768084
Abstract

This article examines the spectrum of metabolic alterations in sepsis and septic shock. The clinical manifestations, neuroendocrine control, and bioenergetics of the "ebb" and "flow" phases of sepsis are reviewed. Characteristic alterations in carbohydrate, fat, and protein metabolism induced by sepsis are outlined. Finally, the implications of these metabolic alterations for the nutritional support of patients with sepsis are discussed.

摘要

本文探讨脓毒症和感染性休克中的代谢改变谱。回顾了脓毒症“潮式”和“流动”期的临床表现、神经内分泌控制及生物能量学。概述了脓毒症引起的碳水化合物、脂肪和蛋白质代谢的特征性改变。最后,讨论了这些代谢改变对脓毒症患者营养支持的意义。

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