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膀胱外翻畸形:最新进展与长期展望。

Exstrophic anomalies: recent advances and long-term outlook.

作者信息

Ngan J H, Mitchell M E

机构信息

University of Washington School of Medicine, Children's Hospital and Medical Center, Division of Pediatric Urology, Seattle 98105, USA.

出版信息

Indian J Pediatr. 1997 May-Jun;64(3):327-38. doi: 10.1007/BF02845202.

Abstract

Exstrophy-epispadias complex has been a difficult disease to treat. As in the minds of the public and most physicians alike, these children are crippled with life-long ailments and multiple operations. Much of the morbidity of this condition relates to failure to preserve urogenital tract function in these children. In recent years, through better understanding of the exstrophic anatomy and improved surgical techniques, complete repair of the exstrophic anomaly has become possible as soon as the child is born. Results of such closure indicate that such repair is not only feasible but mandatory for a successful outcome. Continence rate and cosmetic appearance are superior to the conventional 3-stage technique. Such repair is also socially acceptable as the parents will bring home a normal-looking baby with much fewer operations expected in the future. It is anticipated that complete one-stage exstrophy closure in the newborn period will revolutionize the outcome of all exstrophy patients.

摘要

膀胱外翻-尿道上裂综合征一直是一种难以治疗的疾病。在公众和大多数医生的认知中,这些孩子患有终身疾病且需要多次手术。这种病症的大部分发病率与未能保留这些孩子的泌尿生殖道功能有关。近年来,通过对膀胱外翻解剖结构的更好理解和改进的手术技术,一旦孩子出生,就有可能对膀胱外翻畸形进行完全修复。这种闭合手术的结果表明,这种修复不仅可行,而且对于成功的治疗结果是必不可少的。控尿率和外观优于传统的三阶段技术。这种修复在社会上也是可以接受的,因为父母将带回一个外观正常的婴儿,而且预计未来所需的手术会少得多。预计在新生儿期进行完全一期膀胱外翻闭合手术将彻底改变所有膀胱外翻患者的治疗结果。

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