Kojima M, Wakai K, Kawamura T, Tamakoshi A, Aoki R, Lin Y, Nakayama T, Horibe H, Aoki N, Ohno Y
Department of Preventive Medicine, Nagoya University School of Medicine, Japan.
J Epidemiol. 2000 Mar;10(2):87-93. doi: 10.2188/jea.10.87.
A population-based cohort study was conducted to assess the relationship between total mortality and self-reported sleep patterns as regards not only to sleep duration but also subjective sleep quality. A total of 5,322 inhabitants in Gifu Prefecture, Japan, completed a self-administered questionnaire on health status and lifestyles including habitual sleep patterns, and were followed-up for an average of 11.9 years. Relative risks were computed by using Cox proportional hazards models. Both longer and shorter sleep, compared to 7-8 hour-sleep, was related to significantly increased risk of total mortality in males (relative risk [RR] for > or = 10 hours = 1.94, and RR for < 7 hour = 1.90), but not in females. Females complaining of poor awakening state experienced a higher mortality risk compared to those who woke up normally (RR: 1.97). Males who usually fell asleep easily showed a marginally lower mortality risk compared to those who fell asleep normally (RR: 0.70). Female users of sleeping pills were at an elevated risk (RR: 1.89). These findings were almost unchanged after adjustment for sleep duration and other confounders. Poor self-reported quality of sleep seemed to be associated with an increased risk of mortality independently of sleep duration.
一项基于人群的队列研究开展，以评估全因死亡率与自我报告的睡眠模式之间的关系，该关系不仅涉及睡眠时间，还包括主观睡眠质量。日本岐阜县共有5322名居民完成了一份关于健康状况和生活方式的自填问卷，其中包括习惯性睡眠模式，并接受了平均11.9年的随访。使用Cox比例风险模型计算相对风险。与睡7 - 8小时相比，睡眠时间过长和过短均与男性全因死亡风险显著增加相关（睡眠时间≥10小时的相对风险[RR]=1.94，睡眠时间<7小时的RR = 1.90），但在女性中并非如此。与正常醒来的女性相比，抱怨醒来状态不佳的女性死亡率风险更高（RR：1.97）。与正常入睡的男性相比，通常容易入睡的男性死亡率风险略低（RR：0.70）。服用安眠药的女性风险升高（RR：1.89）。在对睡眠时间和其他混杂因素进行调整后，这些发现几乎没有变化。自我报告的睡眠质量差似乎与死亡率风险增加有关，且独立于睡眠时间。
