Cupitt J M
Department of Anaesthetics, Manchester Royal Infirmary, United Kingdom.
Anaesth Intensive Care. 2000 Apr;28(2):202-4. doi: 10.1177/0310057X0002800215.
A 62-year-old woman with acute promyelocytic leukaemia was treated with all-trans retinoic acid. On day 2 she suffered with dyspnoea and general fatigue. Marked hypoxia suggested the occurrence of retinoic acid syndrome. She underwent endotracheal intubation and mechanical ventilation with the administration of dexamethasone. Her symptoms promptly abated. She was subsequently treated with conventional chemotherapy and achieved complete remission.
一名62岁的急性早幼粒细胞白血病女性患者接受了全反式维甲酸治疗。在治疗第2天,她出现呼吸困难和全身乏力。明显的低氧血症提示维甲酸综合征的发生。她接受了气管插管和机械通气,并给予地塞米松治疗。她的症状迅速缓解。随后她接受了传统化疗并实现了完全缓解。