Huxley N A, Rendall M, Sederer L
The Consolidated Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.
J Nerv Ment Dis. 2000 Apr;188(4):187-201. doi: 10.1097/00005053-200004000-00001.
Pharmacotherapy can improve some of the symptoms of schizophrenia but has limited effect on the social impairments that characterize the disorder and limit functioning and quality of life. Through computerized literature searches and bibliographies of published reports we identified peer reviewed studies of group, family, and individual therapy with schizophrenia and schizoaffective disorder patients. We identified 70 studies: 26 on group therapy, 18 on family therapy, and 11 on individual therapy. Additionally, treatment models were compared in 4 studies and combined in 11 others. Controls were included in 61 and all studies included medication. Benefits in symptoms as well as social and vocational functioning were associated with psychosocial treatments. Family therapy demonstrated the most promising findings and traditional social skills treatment yielded the least robust results. Adjunctive psychosocial treatments augment the benefits of pharmacotherapy and enhance functioning in psychotic disorders. Although these positive results have led to increased enthusiasm about psychosocial treatments for schizophrenia, questions remain about comparative benefits of specific treatment methods and additional benefits of multiple treatments.
药物治疗可以改善精神分裂症的一些症状,但对该疾病所特有的社会功能障碍的作用有限,这些障碍限制了患者的功能和生活质量。通过计算机化文献检索和已发表报告的参考文献,我们确定了针对精神分裂症和分裂情感性障碍患者的团体、家庭和个体治疗的同行评审研究。我们共确定了70项研究:26项关于团体治疗,18项关于家庭治疗,11项关于个体治疗。此外,在4项研究中比较了治疗模式,在另外11项研究中将不同治疗模式进行了组合。61项研究纳入了对照,所有研究均包括药物治疗。心理社会治疗与症状改善以及社会和职业功能改善相关。家庭治疗显示出最有前景的结果,而传统的社交技能治疗产生的效果最不显著。辅助性心理社会治疗可增强药物治疗的益处,并改善精神障碍患者的功能。尽管这些积极结果使人们对精神分裂症的心理社会治疗的热情有所增加,但关于特定治疗方法的相对益处以及多种治疗的额外益处仍存在疑问。