Díaz-Infantes M S, Ruiz-Serrano M J, Martínez-Sánchez L, Ortega A, Bouza E
Servicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario "Gregorio Marañón,", Madrid, Spain.
J Clin Microbiol. 2000 May;38(5):1988-9. doi: 10.1128/JCM.38.5.1988-1989.2000.
The MB/BacT mycobacterium detection system was evaluated for its performance in the susceptibility testing of Mycobacterium tuberculosis. Eighty-three M. tuberculosis isolates were processed. Results for all isoniazid-, rifampin- and streptomycin-susceptible, isoniazid-resistant, and rifampin-resistant M. tuberculosis isolates with the MB/BacT system agreed 100% with those obtained by the agar proportion method. The agreements between the two methods for streptomycin- and ethambutol-resistant isolates were 96.4 and 90.4%, respectively. The susceptibility test results were obtained in 7 days, on average. These data demonstrate that the MB/BacT system is an accurate, nonradiometric method for rapid susceptibility testing of M. tuberculosis.
对MB/BacT分枝杆菌检测系统在结核分枝杆菌药敏试验中的性能进行了评估。对83株结核分枝杆菌分离株进行了处理。使用MB/BacT系统检测所有对异烟肼、利福平和链霉素敏感、异烟肼耐药和利福平耐药的结核分枝杆菌分离株的结果与采用琼脂比例法获得的结果100%一致。两种方法检测对链霉素和乙胺丁醇耐药分离株的一致性分别为96.4%和90.4%。药敏试验结果平均在7天内获得。这些数据表明，MB/BacT系统是一种准确的、非放射性的快速检测结核分枝杆菌药敏的方法。
