Al-Qattan M M
Wound Healing Research Laboratory, King Saud University, Riyadh, Saudi Arabia.
Microsurgery. 2000;20(3):99-104. doi: 10.1002/(sici)1098-2752(2000)20:3<99::aid-micr1>3.0.co;2-y.
This article studies the utilization of the end-to-side neurorrhaphy concept in the prevention and treatment of painful neuromas. A total of 20 rats were divided into 2 groups (10 rats per group). In group A, the tibial nerve was divided and left lying in the subcutaneous tissue. In group B, the cut ends of the tibial nerve were sutured to the adjacent peroneal nerve in an end-to-side fashion. Evaluation was performed 90 days after nerve injury. For group A, the proximal end of the tibial nerve formed a "classic" neuroma and the distal end showed a degenerated nerve. In group B, the proximal end of the tibial nerve formed a "non-classic" neuroma and the nerve healed into the peroneal nerve with continuity of the epineurium of the 2 nerves. The distal end of the tibial nerve in group B showed evidence of axonal regeneration. Preliminary clinical experience utilizing the same technique in the prevention and treatment of painful neuromas of the superficial radial nerve is presented and other techniques of nerve-to-nerve implantation are discussed.
本文研究端侧神经缝合概念在疼痛性神经瘤防治中的应用。将20只大鼠分为2组（每组10只）。A组切断胫神经并使其留置于皮下组织。B组将胫神经的断端以端侧方式缝合至相邻的腓总神经。在神经损伤90天后进行评估。A组中，胫神经近端形成“典型”神经瘤，远端显示神经变性。B组中，胫神经近端形成“非典型”神经瘤，神经愈合进入腓总神经，两条神经的神经外膜连续。B组胫神经远端显示有轴突再生迹象。本文介绍了利用相同技术预防和治疗桡浅神经疼痛性神经瘤的初步临床经验，并讨论了神经对神经植入的其他技术。
