Rogers A, Prügel-Bennett A
ISIS Research Group, Department of Electronics and Computer Science, University of Southampton, Highfield, Southampton, SO17 1BJ, England.
Theor Popul Biol. 2000 Mar;57(2):121-9. doi: 10.1006/tpbi.1999.1446.
In this paper, we extend a previously published model of an evolving finite population of multi-locus organisms, where the dynamics of the evolving system are described by the cumulants of the population efficacy distribution. We consider the case of overlapping generations and compare it to the previously studied case where generations are discrete. In the weak selection limit, we can solve the dynamics analytically and show that the changes in population genetic variance due to stochastic effects-genetic drift-is twice as great when generations overlap. The comparison of the dynamics of the two models shows many of the features seen in the comparison, performed by Moran, of simple one-locus genetic models with overlapping and non-overlapping generations. Studying the dynamics of the two models gives some insights into these comparisons.
在本文中，我们扩展了一个先前发表的关于多位点生物体不断演化的有限种群模型，其中演化系统的动力学由种群功效分布的累积量来描述。我们考虑了世代重叠的情况，并将其与先前研究的世代离散的情况进行比较。在弱选择极限下，我们可以解析地求解动力学，并表明当世代重叠时，由于随机效应——遗传漂变——导致的种群遗传方差的变化是原来的两倍。这两个模型动力学的比较展现出了许多在莫兰对具有重叠和非重叠世代的简单单基因座遗传模型所做比较中看到的特征。对这两个模型动力学的研究为这些比较提供了一些见解。
