Seignalet J, Sany J, Serre H
Rev Rhum Mal Osteoartic. 1975 Feb;42(2):75-83.
Since 1972, several relations have been demonstrated between some HL-A antigens and some articular diseases. The W27 antigen frequency is highly increased in ankylosing spondylitis (88%) and in Reiter disease (78%) compared with controls (5%). In peripheral forms of psoriatic rheumatism, the W17 and HL-A13 antigens are more frequent (24% and 15%) than in healthy subjects (4% and 5%). In central forms of psoriatic rheumatism, there is a relation with W27 (48%) and still, we do not know if this association concerns only spondylitis or also sacro-iletis. The HL-A typing may be useful for the diagnosis of some rheumatologic diseases, when for the diagnosis of ankylosing spondylitis. The relation between W27 and ankylosing spondylitis is cleanly stronger than that between Waaler-Rose reaction and rheumatoid arthritis.
自1972年以来，已证实某些HL - A抗原与某些关节疾病之间存在多种关联。与对照组（5%）相比，强直性脊柱炎（88%）和赖特综合征（78%）中W27抗原频率显著升高。在银屑病性风湿病的外周型中，W17和HL - A13抗原比健康受试者（4%和5%）更常见（分别为24%和15%）。在银屑病性风湿病的中枢型中，与W27存在关联（48%），并且我们仍不清楚这种关联是否仅涉及脊柱炎，还是也涉及骶髂关节炎。HL - A分型对于某些风湿性疾病的诊断可能有用，比如对于强直性脊柱炎的诊断。W27与强直性脊柱炎之间的关联明显强于瓦勒 - 罗斯反应与类风湿关节炎之间的关联。
