Seignalet J, Sany J, Serre H
Sem Hop. 1975 Mar 26;51(15):993-1000.
Since 1972, several relations have been demonstrated between some HL-A antigens and some articular diseases. The W27 antigen frequency is highly increased in ankylosing spondylitis (88%) and in Reiter disease (78%) compared with controls (5%). In peripheral forms of psoriatic rheumatism, the W17 and HL-A13 antigens are more fréquent (24% and 15%) than in healthy subjects (4% and 5%). In central forms of psoriatic rheumatism, there is a relation with W27 (48%) and still, we do not know if this association concerns only spondylitis or also sacro-ileitis. The HL-A typing may be useful for the diagnosis of some rheumatic diseases, when they present atypical appearances. W27 possesses a considerable value for the diagnosis of ankylosing spondylitis. The relation between W27 and ankylosing spondylitis is clearly stronger than that between Waaler-Rose reaction and rheumatoid arthritis.
自1972年以来，已证实某些HL - A抗原与某些关节疾病之间存在多种关联。与对照组（5%）相比，强直性脊柱炎（88%）和赖特综合征（78%）中W27抗原频率显著升高。在银屑病性风湿病的外周型中，W17和HL - A13抗原比健康受试者（4%和5%）更常见（分别为24%和15%）。在银屑病性风湿病的中枢型中，与W27存在关联（48%），不过，我们尚不清楚这种关联是否仅涉及脊柱炎，还是也涉及骶髂关节炎。当某些风湿性疾病表现出非典型外观时，HL - A分型可能有助于其诊断。W27对强直性脊柱炎的诊断具有重要价值。W27与强直性脊柱炎之间的关联明显强于瓦勒 - 罗斯反应与类风湿关节炎之间的关联。
