Van Holde K E, Sahasrabuddhe C G, Shaw B R
Nucleic Acids Res. 1974 Nov;1(11):1579-86. doi: 10.1093/nar/1.11.1579.
A model is proposed for the structure of nuclease-resistant chromatin particles. The model is novel in that it proposes that the DNA in such a particle is wound about a protein core, made up of the hydrophobic regions of histone molecules.
提出了一种耐核酸酶染色质颗粒结构的模型。该模型的新颖之处在于,它提出这种颗粒中的DNA缠绕在一个由组蛋白分子疏水区域组成的蛋白质核心周围。