The effect of head position on the distribution of drops within the nose.

Nose drops are commonly prescribed in the United Kingdom, yet clinicians vary considerably in the instructions they give on how to instill them. This is important because how they are used affects how well they work. In this study, a visual assessment of the intranasal distribution of drops was made using endoscopic examination after the instillation of betamethasone drops containing methylene blue. Drops instilled with the head tipped back were found along the nasal floor and in the nasopharynx, with none visible in the middle meatus or elsewhere on the lateral nasal wall. Drops instilled in Mygind's position or in the praying-to-Mecca position were found predominantly in the middle meatus and on the middle and inferior turbinates. No difference was seen between these two positions in the distribution of drops achieved, and this is likely to lead to similar clinical efficacy. Because Mygind's position is much more comfortable for patients, it should be recommended by all doctors prescribing nose drops.