Pardue M T, Sivak J G
School of Optometry, University of Waterloo, Canada.
Optom Vis Sci. 2000 Apr;77(4):204-10. doi: 10.1097/00006324-200004000-00013.
To examine the role of the ciliary muscle in accommodation and presbyopia.
Sixteen pairs of eyes from donors aged 1 to 107 years were treated with atropine or pilocarpine and then processed for light microscopy. Seven pairs were analyzed for treatment effects, including morphometric measurements of muscle dimensions, muscle fiber group area, and the percentage of connective tissue.
The ciliary muscle shortened in length in response to drug treatment at all ages. The ciliary muscle of older subjects contained greater amounts of connective tissue and was shorter, wider and the internal apical edge moved forward.
This study confirms previous reports that the human ciliary muscle retains its ability to contract throughout the lifespan. However, the ciliary muscle also displayed age-related changes, which may be partly accounted for by the forces exerted from the aging lens and zonules.
研究睫状肌在调节和老花眼中的作用。
对16对年龄在1至107岁供体的眼睛用阿托品或毛果芸香碱进行处理，然后进行光学显微镜检查。分析了7对眼睛的治疗效果，包括肌肉尺寸的形态测量、肌纤维组面积和结缔组织百分比。
在所有年龄段，睫状肌长度均因药物治疗而缩短。老年受试者的睫状肌含有更多的结缔组织，且更短、更宽，内顶端边缘向前移动。
本研究证实了先前的报道，即人类睫状肌在整个生命周期中都保持收缩能力。然而，睫状肌也表现出与年龄相关的变化，这可能部分是由老化晶状体和悬韧带施加的力所导致的。
