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用于会阴修复的可吸收合成缝线与肠线缝合材料对比

Absorbable synthetic versus catgut suture material for perineal repair.

作者信息

Kettle C, Johanson R B

机构信息

Academic Department of Obstetrics and Gynaecology, North Staffordshire Hospital NHS Trust, Maternity Hospital, Newcastle Road, Stoke-on-Trent, Staffordshire, UK, ST4 6QG.

出版信息

Cochrane Database Syst Rev. 2000(2):CD000006. doi: 10.1002/14651858.CD000006.

Abstract

BACKGROUND

Approximately 70% of women will experience some degree of perineal trauma following vaginal delivery and will require stitches. This may result in perineal pain and superficial dyspareunia.

OBJECTIVES

The objective of this review was to assess the effects of absorbable synthetic suture material as compared with catgut on the amount of short and long term pain experienced by mothers following perineal repair.

SEARCH STRATEGY

We searched the Cochrane Pregnancy and Childbirth Group trials register.

SELECTION CRITERIA

Randomised trials comparing absorbable synthetic (polyglycolic acid and polyglactin) with plain or chromic catgut suture for perineal repair in mothers after vaginal delivery.

DATA COLLECTION AND ANALYSIS

Trial quality was assessed independently by two reviewers. Data were extracted by one reviewer and checked by the second reviewer.

MAIN RESULTS

Eight trials were included. Compared with catgut, the polyglycolic acid and polyglactin groups were associated with less pain in first three days (odds ratio 0.62, 95% confidence interval 0.54 to 0.71). There was also less need for analgesia (odds ratio 0.63, 95% confidence interval 0.52 to 0.77) and less suture dehiscence (odds ratio 0.45, 95% confidence interval 0.29 to 0.70). There was no significant difference in long term pain (odds ratio 0.81, 95% confidence interval 0.61 to 1.08). Removal of suture material was significantly more common in the polyglycolic acid and polyglactin groups (odds ratio 2.01, 95% confidence interval 1.56 to 2.58). There was no difference in the amount of dyspareunia experienced by women.

REVIEWER'S CONCLUSIONS: Absorbable synthetic suture material (in the form of polyglycolic acid and polyglactin sutures) for perineal repair following childbirth appears to decrease women's experience of short-term pain. The length of time taken for the synthetic material to be absorbed is of concern. A trial addressing the use of polyglactin has recently been completed and this has been included in this updated review.

摘要

背景

约70%的女性在阴道分娩后会经历一定程度的会阴创伤,需要缝合。这可能导致会阴疼痛和浅表性交困难。

目的

本综述的目的是评估与肠线相比,可吸收合成缝合材料对会阴修复后母亲短期和长期疼痛程度的影响。

检索策略

我们检索了Cochrane妊娠与分娩组试验注册库。

选择标准

比较可吸收合成材料(聚乙醇酸和聚乳酸)与普通或铬制肠线缝合用于阴道分娩后母亲会阴修复的随机试验。

数据收集与分析

试验质量由两名评价员独立评估。数据由一名评价员提取,另一名评价员进行核对。

主要结果

纳入八项试验。与肠线相比,聚乙醇酸和聚乳酸组在产后头三天疼痛较轻(比值比0.62,95%置信区间0.54至0.71)。镇痛需求也较少(比值比0.63,95%置信区间0.52至0.77),缝线裂开较少(比值比0.45,95%置信区间0.29至0.70)。长期疼痛无显著差异(比值比0.81,95%置信区间0.61至1.08)。聚乙醇酸和聚乳酸组缝线拆除更为常见(比值比2.01,95%置信区间1.56至2.58)。女性经历的性交困难程度无差异。

综述作者结论

用于产后会阴修复的可吸收合成缝合材料(聚乙醇酸和聚乳酸缝线形式)似乎可减轻女性的短期疼痛。合成材料吸收所需时间令人担忧。一项关于聚乳酸使用的试验最近已完成,此次更新综述已将其纳入。

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