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硬膜外镇痛与非硬膜外镇痛用于分娩时的疼痛缓解

Epidural versus non-epidural analgesia for pain relief in labour.

作者信息

Howell C J

机构信息

Academic Department of Obstetrics and Gynaecology, North Staffordshire Hospital NHS Trust, Maternity Hospital, Newcastle Road, Stoke on Trent, Staffordshire, UK, ST4 6QG.

出版信息

Cochrane Database Syst Rev. 2000(2):CD000331. doi: 10.1002/14651858.CD000331.

Abstract

BACKGROUND

Epidural analgesia is effective in reducing labour pain, but the possible adverse effects are not clear.

OBJECTIVES

The objective of this review was to assess the effects of epidural analgesia on pain relief and adverse effects in labour.

SEARCH STRATEGY

The Cochrane Pregnancy and Childbirth Group trials register was searched.

SELECTION CRITERIA

Randomised trials comparing epidural analgesia with other forms of analgesia not involving regional blockade, or no intervention.

DATA COLLECTION AND ANALYSIS

Eligibility and trial quality were assessed by one reviewer. Study authors were contacted for additional information.

MAIN RESULTS

Eleven studies involving 3157 women were included. Epidural analgesia was associated with greater pain relief than non-epidural methods, but also with longer first and second stages of labour, an increased incidence of fetal malposition, and increased use of oxytocin and instrumental vaginal deliveries. With new trial data included, no statistically significant effect on caesarean section rates could be identified.

REVIEWER'S CONCLUSIONS: Epidural analgesia appears to be very effective in reducing pain during labour, although there appear to be some potentially adverse effects. Further research is needed to investigate adverse effects and to evaluate the different techniques used in epidural analgesia.

摘要

背景

硬膜外镇痛在减轻分娩疼痛方面有效,但可能的不良反应尚不清楚。

目的

本综述的目的是评估硬膜外镇痛对分娩时疼痛缓解及不良反应的影响。

检索策略

检索了Cochrane妊娠与分娩组试验注册库。

选择标准

比较硬膜外镇痛与其他不涉及区域阻滞的镇痛形式或无干预措施的随机试验。

数据收集与分析

由一名综述作者评估纳入标准和试验质量。与研究作者联系以获取更多信息。

主要结果

纳入了11项研究,涉及3157名女性。硬膜外镇痛与非硬膜外方法相比,疼痛缓解效果更好,但也与第一产程和第二产程延长、胎位异常发生率增加以及缩宫素使用和器械助产阴道分娩的增加有关。纳入新的试验数据后,未发现对剖宫产率有统计学显著影响。

综述作者结论

硬膜外镇痛在减轻分娩疼痛方面似乎非常有效,尽管似乎存在一些潜在的不良反应。需要进一步研究来调查不良反应,并评估硬膜外镇痛中使用的不同技术。

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