Thomas M, Padmini B, Srimathi G, Sundararajan V, Raju B A
Department of Microbiology, PSGIMS and R, Coimbatore.
Indian J Pediatr. 1999 Jan-Feb;66(1):11-4. doi: 10.1007/BF02752342.
In this study, 187 consecutive neonates suspected of having septicaemia were investigated for isolation of micro organisms. Two samples of blood were collected for isolation of aerobes and anaerobes. Cultures were positive in 75 (40%) cases. Aerobic bacteria were the major etiological agent, accounting for 93% of positives including the 8% cases showing polymicrobial etiology. Anaerobic bacteria and Candida species were isolated in 6.6% and 8% of positive cases respectively. Bacteroides fragilis (amongst anaerobic) and Staphylococcus aureus (amongst aerobic) were the predominant organisms isolated. Clinical presentations were not specifically different to distinguish aerobic from anaerobic bacteria. In the present study, 6.6% of bacteremias were due to anaerobes, hence possibility of some of the bactermias being due to anaerobes should be kept in mind while treating cases of neonatal septicaemia. For a complete microbial profile both aerobic and anaerobic cultures should be done.
在本研究中，对187例连续疑似患有败血症的新生儿进行了微生物分离调查。采集两份血样用于需氧菌和厌氧菌的分离。75例（40%）培养结果呈阳性。需氧菌是主要病原体，占阳性病例的93%，其中8%的病例显示为多种微生物病因。厌氧菌和念珠菌分别在6.6%和8%的阳性病例中分离出来。脆弱拟杆菌（厌氧菌中）和金黄色葡萄球菌（需氧菌中）是分离出的主要微生物。临床表现并无特异性差异以区分需氧菌和厌氧菌。在本研究中，6.6%的菌血症由厌氧菌引起，因此在治疗新生儿败血症病例时应考虑到部分菌血症可能由厌氧菌引起。为获得完整的微生物谱，应同时进行需氧和厌氧培养。
