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伴有胎儿苯妥英钠综合征的腹膜后囊性淋巴管瘤。

Retro-peritoneal cystic lymphangioma in association with fetal hydantoin syndrome.

作者信息

Khetarpal R, Halwai G, Marwaha R K, Trehan A, Narasimhan K L, Bhalla A K

机构信息

Department of Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh.

出版信息

Indian J Pediatr. 1999 Mar-Apr;66(2):294-7. doi: 10.1007/BF02761223.

DOI:10.1007/BF02761223
PMID:10798073
Abstract

Antiepileptic drugs are known to be teratogenic. Use of phenytoin during pregnancy can cause various congenital malformations leading to 'fetal hydantoin syndrome'. One such case reported is unique in the sense that it occurred with retroperitoneal cystic lymphangioma, itself a rare condition. Such an association is not described elsewhere.

摘要

已知抗癫痫药物具有致畸性。孕期使用苯妥英可导致各种先天性畸形,进而引发“胎儿妥英综合征”。报道的这样一个病例很独特,因为它伴有腹膜后囊性淋巴管瘤,而腹膜后囊性淋巴管瘤本身就是一种罕见病症。其他地方未描述过这种关联。

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本文引用的文献

1
Lymphoblastic lymphoma following prenatal exposure to phenytoin.产前接触苯妥英钠后发生的淋巴细胞性淋巴瘤。
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Pathogenesis of drug-induced gingival overgrowth. A review of studies in the rat model.药物性牙龈增生的发病机制。大鼠模型研究综述。
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一种与常染色体显性非综合征性听力损失相关的新型 COCH 突变破坏了 vWFA2 结构域的结构稳定性。
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Dilantin-associated lymphadenopathy. Spectrum of histopathologic patterns.
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Multi-institutional study on the teratogenicity and fetal toxicity of antiepileptic drugs: a report of a collaborative study group in Japan.抗癫痫药物致畸性和胎儿毒性的多机构研究:日本一个协作研究小组的报告
Epilepsia. 1980 Dec;21(6):663-80. doi: 10.1111/j.1528-1157.1980.tb04320.x.
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Multilocular cysts of the peritoneum.腹膜多房性囊肿
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Intra-abdominal lymphangiomata.腹腔内淋巴管瘤
Arch Surg. 1966 Aug;93(2):304-8. doi: 10.1001/archsurg.1966.01330020096015.
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Epilepsy and pregnancy: a report from the Oxford Record Linkage Study.癫痫与妊娠:牛津记录链接研究报告
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