Rathi S S, Srinivas M, Grover J K, Mitra D, Vats V, Sharma J D
Department of Pharmacology, All India Institute of Medical Sciences, New Delhi.
Indian J Pediatr. 1999 Sep-Oct;66(5):681-4. doi: 10.1007/BF02726254.
Zinc is an important trace element having a definitive role in the metabolism, growth and development and reproduction. During pregnancy the requirements for zinc increase. This study was designed to evaluate the zinc status of normal women, normal pregnant women and their newborn babies. Forty normal adult females, 40 normal pregnant women and their newborn babies were randomly selected and their serum and hair zinc levels were analysed using atomic absorption spectrophotometer. The mean serum and hair zinc levels in normal women were 69.47 +/- 1.4 micrograms/dl and 147.45 +/- 6.12 micrograms/g respectively. The mean serum and hair zinc levels in normal pregnant women were 69.0 +/- 3.22 micrograms/dl and 142.83 +/- 4.39 micrograms/g respectively while the mean serum (cord blood) and hair levels in normal new born babies were 72.77 +/- 5.14 micrograms/dl and 188.36 +/- 4.12 micrograms/g respectively. There was a significant (p < 0.001) decrease in hair zinc levels during pregnancy. There was a significant (p < 0.05) decrease in zinc levels in new born babies when the time interval between the previous delivery and the present delivery was less than 3.4 years. The results of the present study reinforce the need for zinc supplementation during pregnancy especially if the interval between pregnancies is short.
锌是一种重要的微量元素，在新陈代谢、生长发育及生殖过程中发挥着决定性作用。孕期对锌的需求量会增加。本研究旨在评估正常女性、正常孕妇及其新生儿的锌营养状况。随机选取40名正常成年女性、40名正常孕妇及其新生儿，使用原子吸收分光光度计分析他们的血清和头发锌水平。正常女性的血清锌和头发锌平均水平分别为69.47±1.4微克/分升和147.45±6.12微克/克。正常孕妇的血清锌和头发锌平均水平分别为69.0±3.22微克/分升和142.83±4.39微克/克，而正常新生儿的血清（脐带血）锌和头发锌平均水平分别为72.77±5.14微克/分升和188.36±4.12微克/克。孕期头发锌水平有显著下降（p<0.001）。当上一次分娩与本次分娩的时间间隔小于3.4年时，新生儿的锌水平有显著下降（p<0.05）。本研究结果强化了孕期补充锌的必要性，尤其是在妊娠间隔较短的情况下。
