Stabile J R, Mason K T, Boneta O F
US Army School of Aviation Medicine, Fort Rucker, AL, USA.
Aviat Space Environ Med. 2000 May;71(5):543-4.
From 1988 to 1995, there were five reported cases of hemochromatosis among U.S. Army aviators. Three of the five are presented and discussed. The cases of hereditary hemochromatosis were discovered during unrelated work-ups or from investigation of a positive family history, and not by routine flying duty medical examinations. Recent studies show a prevalence of 5 per 1000 in the general population. This study shows the incidence among Army aviators is 0.296 per 1,000 aviator-years of observation. It is possible that there are cases presently undiagnosed in the Army aviation community. Without screening measures in place, the Army Aviation Branch has greater difficulty diagnosing and treating hereditary hemochromatosis. Heightened awareness and a high clinical index of suspicion are necessary to identify affected patients. Early detection and treatment is essential to prevent long-term end organ damage from iron deposition.
1988年至1995年期间，美国陆军飞行员中有5例血色素沉着症报告病例。现介绍并讨论其中3例。遗传性血色素沉着症病例是在无关的检查过程中或通过对阳性家族史的调查发现的，而非通过常规飞行任务体检发现。最近的研究表明，普通人群中的患病率为千分之五。本研究显示，陆军飞行员中的发病率为每1000名飞行员观察年0.296例。陆军航空部队中目前可能存在未被诊断的病例。由于没有筛查措施，陆军航空部门在诊断和治疗遗传性血色素沉着症方面面临更大困难。提高认识和保持高度的临床怀疑指数对于识别受影响的患者至关重要。早期发现和治疗对于预防铁沉积导致的长期终末器官损害至关重要。
