Homayouni R, Curran T
Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, 38105, USA.
Curr Biol. 2000 May 4;10(9):R331-4. doi: 10.1016/s0960-9822(00)00459-0.
Cyclin-dependent kinase 5 (Cdk5) is much more than its name implies; it plays a role in neuronal migration, neurite outgrowth and degeneration. Recent evidence suggests that Cdk5 regulates neuronal adhesion and cytoskeletal dynamics.
细胞周期蛋白依赖性激酶5(Cdk5)的作用远不止其名称所暗示的那样;它在神经元迁移、轴突生长和退化过程中发挥作用。最近的证据表明,Cdk5调节神经元黏附和细胞骨架动力学。