Olkowski Z L, Wilkins S A
Am J Surg. 1975 Oct;130(4):440-4. doi: 10.1016/0002-9610(75)90481-x.
Percentage and levels of circulating T-lymphocytes were studied in forty-six patients with squamous cell carcinoma of the head and neck before and/or after treatment and compared with control values obtained in fifty-one healthy volunteers. Mean percentages of circulating T-cells and mean T-cell levels in cancer patients prior to treatment were significantly lower than control values. After surgery or radiation therapy the mean percentage of T-cells remained lower in comparison with that of the controls whereas T-cell levels in patients evaluated after surgical treatment increased in comparison with pretreatment values and were not significantly different from those of the controls.
对46例头颈部鳞状细胞癌患者治疗前和/或治疗后的循环T淋巴细胞百分比及水平进行了研究,并与51名健康志愿者的对照值进行了比较。癌症患者治疗前循环T细胞的平均百分比和平均T细胞水平显著低于对照值。手术或放疗后,T细胞的平均百分比与对照组相比仍然较低,而手术治疗后评估的患者T细胞水平与治疗前值相比有所增加,且与对照组无显著差异。